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Review of local wound management for scleroderma-associated digital ulcers

Abstract

Digital ulcers (DU) are a common clinical problem in systemic sclerosis (SSc); however, there is no standardization of local wound care protocols for management of these lesions. There is a well-recognized need to develop and standardize non-pharmacological management of DU in patients with SSc, and to adopt these protocols in future clinical trials that focus on DU healing. The purpose of this review is to outline the types of DU that occur in SSc, and provide an update on the principles of wound management for these lesions based on the current literature and expert opinion.

Post author correction

Article Type: REVIEW

Article Subject: Treatment

DOI:10.5301/jsrd.5000268

Authors

Nicholas Lebedoff, Tracy M. Frech, Victoria K. Shanmugam, Aryeh Fischer, Daniel Erhardt, Jason Kolfenbach, Kevin Kohler, Kurt Bernhisel, Giavonni M. Lewis

Article History

Disclosures

Financial support: Dr. Frech K23: Research reported in this publication was supported by the National Institute of Arthritis and Musculoskeletal and Skin Diseases of the National Institutes of Health under Award Number K23AR067889. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health. VA Merit: The project described was supported by Award Number I01CX001183 from the Clinical Science Research & Development Service of the VA Office of Research and Development.
Conflict of interest: None of the authors has financial interest related to this study to disclose.

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Authors

Affiliations

  • Department of Internal Medicine, University of Utah, Salt Lake City, UT - USA
  • Division of Rheumatology, Department of Internal Medicine, University of Utah, Salt Lake City, UT - USA
  • Division of Rheumatology, The George Washington University School of Medicine and Health Sciences, Washington DC - USA
  • Division of Rheumatology, Department of Internal Medicine, University of Colorado School of Medicine, Denver, CO - USA
  • Department of Physical Medicine and Rehabilitation, University of Utah, Salt Lake City, UT - USA
  • Division of Emergency Medicine, Department of Surgery, University of Utah, Salt Lake City, UT - USA
  • Division of General Surgery, Department of Surgery, University of Utah, Salt Lake City, UT - USA

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